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Contact information

Email
simon.kyle@ndcn.ox.ac.uk

Simon Kyle

MA (First Class Hons.), PhD

Professor of Experimental and Clinical Sleep Research

Programme Director, The Oxford Online Programme in Sleep Medicine
Co-Director, Experimental and Clinical Sleep Medicine
Honorary Member, Department of Psychiatry
Senior Research Fellow, Somerville College
Theme Co-Lead, Better Sleep, NIHR Oxford Health Biomedical Research Centre

Sleep, sleep disorders and their treatment

I have specific research interests in the aetiology and management of sleep disturbance and the interaction between sleep disturbance and mental health.

My research is funded by The National Institute for Health and Care Research (NIHR) Oxford Health Biomedical Research Centre (BRC), Health Technology Assessment (HTA) Programme, Programme Grants for Applied Research (PGfAR), Efficacy and Mechanisms Evaluation (EME) Programme and the Wellcome Trust.

Research groups

Experimental and Clinical Sleep Medicine

Websites

Kavli Institute for Nanoscience Discovery
Research centre

Key publications

Emotional Processing Following Digital Cognitive Behavioral Therapy for Insomnia in People With Depressive Symptoms

Tamm S. et al, (2025), JAMA Network Open, 8, e2461502 - e2461502

Clinical effectiveness of DREAMS START (Dementia Related Manual for Sleep; Strategies for Relatives) versus usual care for people with dementia and their carers: a single-masked, phase 3, parallel-arm, superiority randomised controlled trial

Rapaport P. et al, (2024), The Lancet Healthy Longevity, 5, 100635 - 100635

The sleep–circadian interface: A window into mental disorders

Meyer N. et al, (2024), Proceedings of the National Academy of Sciences, 121

The European Insomnia Guideline: An update on the diagnosis and treatment of insomnia 2023

Riemann D. et al, (2023), Journal of Sleep Research, 32

Clinical and cost-effectiveness of nurse-delivered sleep restriction therapy for insomnia in primary care (HABIT): a pragmatic, superiority, open-label, randomised controlled trial

KYLE S., (2023), The Lancet

The effect of sleep continuity disruption on multimodal emotion processing and regulation: a laboratory‐based, randomised, controlled experiment in good sleepers

Reid MJ. et al, (2023), Journal of Sleep Research, 32

The effect of sleep restriction therapy for insomnia on sleep pressure and arousal: a randomized controlled mechanistic trial

Maurer LF. et al, (2022), Sleep, 45

Biological and clinical insights from genetics of insomnia symptoms

Lane JM. et al, (2019), Nature Genetics, 51, 387 - 393

Sleep and cognitive performance: cross-sectional associations in the UK Biobank

Kyle SD. et al, (2017), Sleep Medicine, 38, 85 - 91

A Randomized, Placebo-Controlled Trial of Online Cognitive Behavioral Therapy for Chronic Insomnia Disorder Delivered via an Automated Media-Rich Web Application

Espie CA. et al, (2012), Sleep, 35, 769 - 781

Recent publications

Digital Cognitive Behavioural Therapy for Insomnia Compared to Sleep Health Education in Older Adults With Mild Cognitive Impairment and Insomnia: A Feasibility Randomised Controlled Trial

Hoyos CM. et al, (2026), Journal of Sleep Research, 35

Sleep and circadian health in the UK Biobank: report on the 2023 sleep questionnaire enhancement

Tse KYK. et al, (2026), SLEEP, 49

Insights from nine nights of self-applied, low-density sleep EEG during sleep restriction therapy: a proof-of-concept evaluation

Stanyer EC. et al, (2026)

Untangling the mechanisms of sleep restriction therapy

Stanyer EC. et al, (2026), SLEEPJ, 49

The DREAMS START intervention for sleep in dementia: Long‐term follow‐up of a randomized controlled trial

Rapaport P. et al, (2026), Alzheimer's & Dementia, 22

Longitudinal cardiorespiratory wearable sleep staging in the home

Davidson S. et al, (2026), Frontiers in Neuroscience, 20

Sleep Improvement for Metabolic Health: A Feasibility Trial of a Digital Sleep Treatment in People With Insomnia and Non‐Diabetic Hyperglycaemia

Sharman R. et al, (2026), Journal of Sleep Research

The clinical and cost-effectiveness of improving sleep via carer delivered strategies in people with dementia: the DREAMS START parallel multi-centre RCT

Rapaport P. et al, (2026), Health Technology Assessment, 1 - 26

Associations between shift work patterns and sleep disturbance: an analysis of cross-sectional data from UK Biobank

Li X. et al, (2026), BMJ Open, 16, e102976 - e102976

THE IMPACT OF WORKING NIGHTS OR ROTATING SHIFTS ON SLEEP-A CROSS-SECTIONAL SURVEY

Sugavanam T. et al, (2026), SLEEP MEDICINE, 138

More publications