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Contact information

Email
simon.kyle@ndcn.ox.ac.uk

Simon Kyle

MA (First Class Hons.), PhD

Professor of Experimental and Clinical Sleep Research

Programme Director, The Oxford Online Programme in Sleep Medicine
Co-Director, Experimental and Clinical Sleep Medicine
Honorary Member, Department of Psychiatry
Senior Research Fellow, Somerville College

Sleep, sleep disorders and their treatment

I have specific research interests in the aetiology and management of sleep disturbance and the interaction between sleep disturbance and mental health.

My research is funded by The National Institute for Health and Care Research (NIHR) Oxford Health Biomedical Research Centre (BRC), Health Technology Assessment (HTA) Programme, Programme Grants for Applied Research (PGfAR), Efficacy and Mechanisms Evaluation (EME) Programme and the Wellcome Trust.

Research groups

Experimental and Clinical Sleep Medicine

Websites

Kavli Institute for Nanoscience Discovery
Research centre

Key publications

Clinical and cost-effectiveness of nurse-delivered sleep restriction therapy for insomnia in primary care (HABIT): a pragmatic, superiority, open-label, randomised controlled trial
Journal article

KYLE S., (2023), The Lancet
The sleep-circadian interface: a window into mental disorders
Journal article

Meyer N. et al, (2024), Proceedings of the National Academy of Sciences of USA
Biological and clinical insights from genetics of insomnia symptoms
Journal article

Lane JM. et al, (2019), Nature Genetics, 51, 387 - 393
The effect of sleep restriction therapy for insomnia on sleep pressure and arousal: a randomized controlled mechanistic trial
Journal article

Maurer LF. et al, (2021), Sleep
A Randomized, Placebo-Controlled Trial of Online Cognitive Behavioral Therapy for Chronic Insomnia Disorder Delivered via an Automated Media-Rich Web Application
Journal article

Espie CA. et al, (2012), Sleep, 35, 769 - 781
The effect of sleep continuity disruption on multimodal emotion processing and regulation: a laboratory-based, randomized, controlled experiment in good sleepers.
Journal article

Reid M. et al, (2022), Journal of Sleep Research
Sleep and cognitive performance: cross-sectional associations in the UK Biobank
Journal article

Kyle SD. et al, (2017), Sleep Medicine, 38, 85 - 91
The European Insomnia Guideline: An update on the diagnosis and treatment of insomnia 2023.
Journal article

Riemann D. et al, (2023), J Sleep Res, 32

Recent publications

Clinical effectiveness of DREAMS START (Dementia Related Manual for Sleep; Strategies for Relatives) versus usual care for people with dementia and their carers: a single-masked, phase 3, parallel-arm, superiority randomised controlled trial
Journal article

KYLE S., (2024), The Lancet Healthy Longevity
Nurse-delivered sleep restriction therapy to improve insomnia disorder in primary care: the HABIT RCT
Journal article

Kyle SD. et al, (2024), Health Technology Assessment, 1 - 107
The effect of single-component sleep restriction therapy on depressive symptoms: A systematic review and meta-analysis.
Journal article

Tse KYK. et al, (2024), J Sleep Res
A systematic review of the performance of actigraphy in measuring sleep stages.
Journal article

Yuan H. et al, (2024), J Sleep Res
Clinical and cost-effectiveness of DREAMS START (Dementia RElAted Manual for Sleep; STrAtegies for RelaTives) for people living with dementia and their carers: a study protocol for a parallel multicentre randomised controlled trial.
Journal article

Rapaport P. et al, (2024), BMJ Open, 14
Self-supervised learning of accelerometer data provides new insights for sleep and its association with mortality
Journal article

Yuan H. et al, (2024), npj Digital Medicine
The sleep-circadian interface: a window into mental disorders
Journal article

Meyer N. et al, (2024), Proceedings of the National Academy of Sciences of USA
Nurse-delivered sleep restriction therapy in primary care for adults with insomnia disorder: a mixed-methods process evaluation
Journal article

Armstrong S. et al, (2024), British Journal of General Practice, 74, e34 - e40
Causal Association Between Subtypes of Excessive Daytime Sleepiness and Risk of Cardiovascular Diseases.
Journal article

Goodman MO. et al, (2023), J Am Heart Assoc
The European Insomnia Guideline: An update on the diagnosis and treatment of insomnia 2023.
Journal article

Riemann D. et al, (2023), J Sleep Res, 32

More publications