Postdoctoral Research Associate
My previous research interest in amyloid structures brought me to the Tofari’s lab. My primary aim in my Ph.D. was to investigate the potential of flaviviral and coronaviral proteins to form amyloid aggregates and their interaction with hallmark proteins. Here, I am working on the clearance of alpha-synuclein aggregates using Protac molecules. The distant goal is to identify drug candidates to be useful in Parkinson’s disease.
Amyloidogenic proteins in the SARS-CoV and SARS-CoV-2 proteomes
Bhardwaj T. et al, (2023), Nature Communications
Potential of ADAM 17 Signal Peptide To Form Amyloid Aggregates in Vitro
Bhardwaj T. and Giri R., (2023), ACS Chemical Neuroscience
Investigating the conformational dynamics of Zika virus NS4B protein.
Bhardwaj T. et al, (2022), Virology, 575, 20 - 35
Reprofiling of approved drugs against SARS-CoV-2 main protease: an in-silico study.
Kumar P. et al, (2022), J Biomol Struct Dyn, 40, 3170 - 3184