Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

The term autoimmune epilepsy was coined in Oxford and we continue to be a leading centre for research into this area (please see Oxford Autoimmune Neurology Group for full details).

In particular we are interested in the role of LGI1, CASPR2, NMDA and GAD antibodies in epilepsy.

Caption: Jerks affecting the arm, leg and face, so termed faciobrachial dystonic seizures are considered pathognomonic of LGI1 associated epilepsy, one of the autoimmune epilepsies that we are studying here in Oxford

Selected publications

The importance of early immunotherapy in patients with faciobrachial dystonic seizures

Journal article

Thompson J. et al, (2018), Brain, 141, 348 - 356

Focal CA3 hippocampal subfield atrophy following LGI1 VGKC-complex antibody limbic encephalitis

Journal article

Miller TD. et al, (2017), Brain, 140, 1212 - 1219

Pathognomonic seizures in limbic encephalitis associated with anti-LGI1 antibodies

Journal article

Sen A. et al, (2014), The Lancet, 383, 2018 - 2018

Faciobrachial dystonic seizures precede Lgi1 antibody limbic encephalitis

Journal article

Irani SR. et al, (2011), Annals of Neurology, 69, 892 - 900

Epilepsy: an autoimmune disease?

Journal article

PALACE J., (2000), Journal of Neurology, Neurosurgery & Psychiatry, 69, 711 - 714