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Pietro Luca Ratti

MD PhD


Senior Clinical Research Fellow and Consultant Neurologist

  • Clinical Lead, Adult Neurology Sleep Unit, Department of Clinical Neurophysiology, John Radcliffe Hospital, Oxford University Hospitals NHS Foundation Trust

Clinical Sleep Medicine and Sleep Research

CLINICAL SLEEP NEUROSCIENCE

We spend approximately one-third of our lives sleeping. What fascinates me most about this intriguing process is how the brain restores its energy and prepares both itself and the whole body for the day ahead.

As a clinician and sleep neuroscientist, I am aware of how vital sleep is for wellbeing and health. This is why I have dedicated my professional life to improving my patients' sleep, focusing my research on better understanding this essential biological function and how to treat sleep disturbances.

My clinical expertise in the different facets of sleep medicine and neurodegenerative disorders continues to inspire my research, addressing questions that are both clinically relevant and have the potential to improve patient care and outcomes.

I am also an enthusiastic teacher and find teaching to be an enriching experience that brings fresh insights and new perspectives to both research and clinical practice for students and mentors alike.

Research focus

Empowering patients to cope with their sleep problems with creative art-based methods 

Sleep and wake disturbances in neurodegenerative disorders

REM sleep behaviour disorder

Sleep and motor performance in Parkinson's disease

Insomnia disorder

New technologies for sleep medicine and neurodegenerative disease

ABOUT MYSELF

I trained in Medicine and specialised in Neurology in Milan, Italy, and in Sleep Medicine in Barcelona, Spain.

I completed my PhD in Neuroscience, Language and Cognition at the University of Toulouse, France, with a thesis on sleep disorders in Parkinson's disease, and a clinical fellowship in Adult Epilepsy at the University of Montreal, Canada.

I have founded I currently run an online sleep clinic ("Al Centro del Sonno") and I am research associate at the Neurocenter of Southern Switzerland, Ente Ospedaliero Cantonale, Lugano, Switzerland, where I conduct a research programme on sleep in Parkinson's disease.

I moved to Oxford in 2024 and since July 2025 I am leading the Adult Neurology Sleep Service at the Department of Clinical Neurophysiology of the Oxford University Hospitals NHS Foundation Trust, part of the Oxford Sleep Centre.