CRISPR Workshop
DATE AND VENUE
Thursday 4 July 2024, 1.30-6.30pm, TS Eliot Theatre, Merton College, Oxford.
Sponsored by the NIHR Oxford Biomedical Research Centre's Gene and Cell Therapy theme.
REGISTRATION
This event is open to Oxford University research staff and graduate students. (An Oxford University Single Sign-On is required for access to the registration form.) PLEASE NOTE THAT ONLINE REGISTRATION IS NOW CLOSED AS ALL SEATS IN THE AUDITORIUM HAVE BEEN FILLED.
PROGRAMME
| 13.15 | REGISTRATION | |
| 14.00 | Robert MacLaren, Theme Leader for Gene and Cell Therapy, NIHR Oxford Biomedical Research Centre | Welcoming address |
| 14.05 | SESSION 1: CRISPR-based gene editing, activation, silencing and epigenetic applications (Chair: Sophia Bellingrath) | |
| Sophia Bellingrath, DPhil Student, Nuffield Department of Clinical Neurosciences | Assessment and correction of two splice site mutations in CRB1 with RNA editing | |
| Sam Jones, DPhil Student, Radcliffe Department of Medicine | Base editing for the allele-specific silencing of dominant negative genetic variants in inherited cardiomyopathies | |
| Celia Sourd, Postdoctoral Research Scientist, Nuffield Department of Clinical Neurosciences | Gene editing approaches for myotubular myopathy | |
| Benjamin Ng, DPhil Student, Nuffield Department of Clinical Neurosciences | Applications of CRISPR activation in the eye | |
| Bora Ozcan, Research Assistant, Radcliffe Department of Medicine | Epigenetic silencing of therapeutic targets in primary T cells | |
| Weijiao Zhang, Postdoctoral Research Scientist, Radcliffe Department of Medicine | Developing a genome editing approach for immune-mediated diseases | |
| Georgie Fisher, Research Assistant, Genome Engineering Oxford, Sir William Dunn School of Pathology | A novel co-selection system to enrich for prime editing events in mammalian cells | |
| 15.30 | COFFEE BREAK | |
| 16.00 | SESSION 2: Delivery strategies for CRISPR systems and clinical translation of CRISPR technologies (Chair: Connie Han) | |
| Connie Han, DPhil Student, Nuffield Department of Clinical Neurosciences |
Chemically modified CRISPR sgRNA for non-viral delivery | |
| Filipa Simões, Group Leader, Department of Physiology, Anatomy and Genetics | Next-Gen cardiac regeneration: Cas9-mediated gene editing via electroporation of injured zebrafish hearts | |
| Jakob Hansen Haldrup, Postdoctoral Research Scientist, Radcliffe Department of Medicine | Stealth delivery of gene editing systems by repurposing human proteins and fusogens | |
| Dhanu Gupta, Postdoctoral Research Scientist, Department of Paediatrics | Engineered extracellular vesicles for gene editing applications | |
| Yavor Bozhilov, Postdoctoral Research Scientist, Radcliffe Department of Medicine | Developing a stable human haematopoietic stem cell culture system for CRISPR/Cas9-based genome editing | |
| Stephan Sanders, Professor of Neurogenetics, Department of Paediatrics | Facilitating reprogramming of genome editing therapies at scale | |
| 17.15 | DRINKS AND CANAPÉS |