Senior Postdoctoral Fellow
My research is focussed on identification of disease causing pathways and the role of MS susceptibility variants with an emphasis on non-immune cell mediated mechanisms. I am also involved in international collaborations to explore novel cutting edge technology in order to elucidate disease progression and neuroinflammation.
I have a long-standing interest in cellular immunology, especially on how adaptive immune responses are generated upon activation of innate immune cells.
I obtained my PhD at the Max-Planck Institute for Infection Biology with Prof. S.H.E. Kaufmann in Berlin, Germany where I analyzed vaccine-induced antigen-specific T cell responses in the lung.
I then worked as a Postdoctoral Researcher with Prof. R. Lang at the Institute for Clinical Microbiology, Immunology and Hygiene at the University Hospital Erlangen, Germany. There I characterized glycolipid-mediated activation of the C-type lectin receptor Mincle, for which I was awarded a young investigators ELAN grant from the University Hospital Erlangen in 2013.
I joined Professor Lars Fugger's group in 2014 and am now working as a senior postdoctoral scientist.
Dual transcriptome of the immediate neutrophil and Candida albicans interplay
Niemiec MJ. et al, (2017), BMC Genomics, 18
Resolving TYK2 locus genotype-to-phenotype differences in autoimmunity
Dendrou CA. et al, (2016), Science Translational Medicine, 8, 363ra149 - 363ra149
The Mincle-Activating Adjuvant TDB Induces MyD88-Dependent Th1 and Th17 Responses through IL-1R Signaling
Desel C. et al, (2013), PLoS ONE, 8, e53531 - e53531
Recombinant BCG ΔureC hly+ Induces Superior Protection Over Parental BCG by Stimulating a Balanced Combination of Type 1 and Type 17 Cytokine Responses
Desel C. et al, (2011), The Journal of Infectious Diseases, 204, 1573 - 1584
Targeting Syk-Card9-activating C-type lectin receptors by vaccine adjuvants: Findings, implications and open questions
Lang R. et al, (2011), Immunobiology, 216, 1184 - 1191