Research groups
Christiane Desel
Senior Postdoctoral Fellow
My Research
My research is focussed on identification of disease causing pathways and the role of MS susceptibility variants with an emphasis on non-immune cell mediated mechanisms. I am also involved in international collaborations to explore novel cutting edge technology in order to elucidate disease progression and neuroinflammation.
About me
I have a long-standing interest in cellular immunology, especially on how adaptive immune responses are generated upon activation of innate immune cells.
I obtained my PhD at the Max-Planck Institute for Infection Biology with Prof. S.H.E. Kaufmann in Berlin, Germany where I analyzed vaccine-induced antigen-specific T cell responses in the lung.
I then worked as a Postdoctoral Researcher with Prof. R. Lang at the Institute for Clinical Microbiology, Immunology and Hygiene at the University Hospital Erlangen, Germany. There I characterized glycolipid-mediated activation of the C-type lectin receptor Mincle, for which I was awarded a young investigators ELAN grant from the University Hospital Erlangen in 2013.
I joined Professor Lars Fugger's group in 2014 and am now working as a senior postdoctoral scientist.
Recent publications
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Dual transcriptome of the immediate neutrophil and Candida albicans interplay
Journal article
Niemiec MJ. et al, (2017), BMC Genomics, 18
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Resolving TYK2 locus genotype-to-phenotype differences in autoimmunity
Journal article
Dendrou CA. et al, (2016), Science Translational Medicine, 8, 363ra149 - 363ra149
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The Mincle-Activating Adjuvant TDB Induces MyD88-Dependent Th1 and Th17 Responses through IL-1R Signaling
Journal article
Desel C. et al, (2013), PLoS ONE, 8, e53531 - e53531
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Recombinant BCG ΔureC hly+ Induces Superior Protection Over Parental BCG by Stimulating a Balanced Combination of Type 1 and Type 17 Cytokine Responses
Journal article
Desel C. et al, (2011), The Journal of Infectious Diseases, 204, 1573 - 1584
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Targeting Syk-Card9-activating C-type lectin receptors by vaccine adjuvants: Findings, implications and open questions
Journal article
Lang R. et al, (2011), Immunobiology, 216, 1184 - 1191