Biography
I joined the Oxford neurology registrar rotation in 2020, and started my DPhil under the supervision of Dr AG Thompson and Professor MR Turner in 2022.
Training and qualifications
- BSc 2013 Imperial College London
- MBBS 2015 Imperial College London
- MRCP 2018 Royal College of Physicians
Colleges
David Lester
Clinical Research Fellow
Research groups
DPhil key hypotheses
- Clinical heterogeneity in amyotrophic lateral sclerosis (ALS) reflects differences in underlying disease biology
- These differences in disease biology are reflected in the cerebrospinal fluid (CSF) proteome
- Integrated analysis of the CSF proteome will allow separation of patients with ALS into distinct, biologically-relevant clusters linked to key aspects of clinical heterogeneity
- Clusters can be used as a means to stratify patients to improve prediction of disease progression and, ultimately, response to more bespoke drug treatment