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Funding

David Lester

Clinical Research Training Fellow

Biography

I qualified in medicine with distinction from Imperial College London in 2015, completed my general medicine rotations in South West England and then joined the Oxford neurology registrar training programme in 2020.

Research

I am doing a jointly-funded MRC and MND Association DPhil (PhD) under the supervision of Dr Alex Thompson, Professor Martin Turner and Dr Avi Taylor.

I am interested in the variation between people with motor neuron disease (MND, or amyotrophic lateral sclerosis, ALS). There are stark differences in how MND affects people young and old, their prognoses, cognitive changes, and patterns of weakness.

I use clinical data and data from experiments on patients' blood and cerebrospinal fluid samples to see if these differences hold biological clues about MND. I am particularly interested in machine learning, survival analysis and joint modelling.

Social media

Recent publications

More publications

College