Senior Postdoctoral Scientist
Gurman’s research primarily focuses on understanding the role of genetic interactions and natural killer (NK) cells in immune-mediated diseases. She joined Prof Lars Fugger’s group in 2009 and her research aims to tease apart the complexity of NK cell receptor genes in modulating susceptibility to disease. She also has an interest in understanding the mechanisms responsible for the diversity in HLA-C expression, which is an important determinant in influencing disease outcome and efficacy of the immune response.
Gurman is a visiting research fellow at the Broad Institute of MIT and Harvard, Boston and has fostered collaborative research. She is a recipient of the Radcliffe Department of Medicine 2016 excellence award. Gurman enjoys teaching and is a lecturer on the MSc Integrated Immunology course at the University of Oxford, and a Research Associate at St Catherine’s College, Oxford.
Gurman obtained her PhD from the University of Cambridge under the supervision of Prof Hill Gaston, for which she received the Overseas Research Scholarship and the Cambridge Commonwealth Trust Scholarship. During her doctoral studies, Gurman identified novel splice variants of FOXP3 and investigated the role of these splice variants in human regulatory T cells. Prior to her PhD, Gurman completed a MSc in Human Molecular Genetics from Imperial College London with a full scholarship awarded by the Inlaks Foundation and Imperial College London.
Mouse fetal growth restriction through parental and fetal immune gene variation and intercellular communications cascade
KAUR G. et al, (2022), Nature Communications
Identification of early neurodegenerative pathways in progressive multiple sclerosis
Kaufmann M. et al, (2022), Nature Neuroscience
Identifying CNS-colonizing T cells as potential therapeutic targets to prevent progression of multiple sclerosis
Kaufmann M. et al, (2021), Med, 2, 296 - 312.e8
Structural and regulatory diversity shape HLA-C protein expression levels
Kaur G. et al, (2017), Nature Communications, 8
locus genotype-to-phenotype differences in autoimmunity
Dendrou CA. et al, (2016), Science Translational Medicine, 8