Research groups
Colleges
Sources of Funding
Jonathan Attwood
MA (Oxon) BMBCh PGCert AFHEA
DPhil Student & MRC Clinical Research Training Fellow
- Clinical Neurosciences DPhil Student
- Clinical Research Training Fellow (Neurology)
- Honorary Clinical Teaching Fellow
Biography
Jonathan completed his medical training at the University of Oxford in 2017, before pursuing a clerkship in Neurology at Harvard Medical School and an attachment in Neurosurgery at the University of California San Francisco.
After graduating, Jonathan performed research alongside his clinical training as an Honorary Research Fellow in NDCN, publishing in the fields of neurology, neurosurgery, neuropsychology, and histopathology. He served as Research Lead on the national committee of the Neurology and Neurosurgery Special Interest Group, and has presented his research to the British Neuroscience Association, the Federation of European Neuroscience Societies, and the World Federation of Neurology.
In 2021, he gained an NIHR Academic Clinical Fellowship to combine specialty training in neurology with neuroscience research in Oxford. In 2023, he was awarded an MRC Clinical Research Training Fellowship to pursue a DPhil in Clinical Neurosciences. His research supervisors are Professor Gabriele De Luca and Professor Edward de Haan, and he is mentored by Professor Margaret Esiri.
Research
My research addresses the long-term effects of traumatic brain injuries.
A traumatic brain injury is a head injury which results in symptoms of brain dysfunction. One in two people will experience a traumatic brain injury in their lifetime.
Suffering a traumatic brain injury significantly increases the risk of developing common neurological conditions in later life, including dementia, stroke, and epilepsy, as well as common psychiatric disorders such as depression. More research is needed to understand why this is the case and what can be done to reduce these risks.
Recent studies have revealed important insights into the long term effects of certain types of brain injuries, especially concussion. However, we still know very little about other types of brain injuries, including the most severe cases which involve direct damage to the brain caused by injuries that penetrate the skull.
To address this, I am studying a uniquely detailed collection of information gathered over the lifetime of several thousand veterans who survived for decades after penetrating brain injuries. I am working to answer the following questions:
1. What are the long-term effects of penetrating brain injuries on physical health, mental health, and life expectancy?
2. What can we learn about the processes which cause dementia from the study of brain tissue donated by survivors of penetrating brain injuries?
3. What are the specific problems faced by people living with damage to particular regions of the brain after penetrating brain injuries?
By answering these questions I hope to contribute towards improving the lives of people affected by traumatic brain injuries.
Recent publications
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Clinical diagnosis of LGI1 antibody encephalitis in an 83-year-old woman
Journal article
Attwood JE. et al, (2021), BMJ Case Reports, 14, e237398 - e237398
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Mixed Olfactory Neuroblastoma and Adenocarcinoma with In Situ Neuroendocrine Hyperplasia
Journal article
Attwood JE. et al, (2020), Head and Neck Pathology, 14, 792 - 798
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London Trauma Conference 2019
Conference paper
(2020), Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 28
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Evaluation of nationwide referral pathways, investigation and treatment of suspected cauda equina syndrome in the United Kingdom
Journal article
Fountain DM. et al, (2019), British Journal of Neurosurgery, 33, 624 - 634
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Sir Hugh Cairns: a pioneering collaborator
Journal article
Attwood JE. et al, (2019), Acta Neurochirurgica, 161, 1491 - 1495
Teaching
Jonathan has taught regularly at Oxford Medical School for more than five years. He is an Honorary Clinical Teaching Fellow in NDCN, a Medical Tutor at Harris Manchester College, and an Associate Fellow of the Higher Education Academy.
His teaching experience ranges from anatomy demonstration to resuscitation training, and he has co-supervised a number of successful student research and education projects. He now provides regular clinical tutorials, seminars, and lectures in clinical neuroscience and also contributes towards teaching in medical humanities. In 2022, he was recognised by the Medical Sciences Division as a Tutor of the Term.
In 2023, Jonathan led the design and delivery of a new medical student teaching program entitled Sports Neurology, Psychiatry, and Rehabilitation. This program addresses the currently unmet need for medical student training in the recognition and management of concussion and its complications. This initiative is part of a broader mission to raise awareness about concussion and brain injuries, and to provide training which equips healthcare professionals to practice with competence and confidence at the increasingly important interface between neurology and sport.
Sport
As a student I played hockey for the University of Oxford and cricket for Oxford Medical School. As a doctor I still enjoy playing tennis and run regularly. I have cycled from London to Paris and competed in the Paris Marathon, Blenheim Palace Triathlon, and the Oxford Half Marathon.