BSc (Hons), MSc
I am a DPhil student in the Sleep and Circadian Neuroscience institute (Nuffield Department of Clinical Neurosciences) and in the Department of Psychiatry. My work is supervised by Dr Simon Kyle, Dr Kate Saunders, and Prof Colin Espie, and is funded by the Medical Research Council Doctoral Training Partnership and the Nuffield Department of Clinical Neurosciences.
My primary research interest is the interplay between sleep and affect in clinical populations, specifically bipolar disorder. From its earliest conceptualisation as a psychiatric disorder in 1921 by Emil Kraepelin, bipolar disorder was diagnostically associated with a range of sleep problems. Now, 100 years later, the causal ordering of sleep impairments and bipolar pathology has yet to be thoroughly examined. So, my DPhil research explores: a) early sleep and circadian endophenotypes of bipolar disorder in high-risk individuals, b) the putative mechanism linking sleep deprivation and affective instability, and c) the therapeutic effects of sleep and circadian rhythms psychotherapies in bipolar patients.
I am also interested in student mental health, working alongside Prof Anne Duffy in the U-Flourish project, looking at mental wellbeing predictors of academic achievement. Finally, I am a huge advocate of open science and always keen to talk about improvements in biomedical research practices.
Mitchell LJ. et al, (2019), Sleep Medicine Reviews, 47, 90 - 102
van der Zweerde T. et al, (2019), Sleep Medicine Reviews, 48, 101208 - 101208
Duffy A. et al, (2020), BJPsych Open, 6
Kyle SD. et al, (2020), Sleep, 43