Lucy Farrimond

I am an Academic Clinical Lecturer in NDCN and Honorary Neurology Registrar for Oxford University Hospitals NHS Foundation Trust. My research takes place within the Oxford Motor Neuron Disease Centre. I have a specific interest in mechanisms of motor neuron degeneration in motor neuron disease, also known as amyotrophic lateral sclerosis (ALS).

After qualifying in medicine (BM BCh) with distinction from the University of Oxford in 2012, I was awarded an Academic Foundation post in Oxford where I first joined Professor Kevin Talbot’s research group studying mouse models of ALS. I subsequently gained an NIHR Academic Clinical Fellowship in Neurology where I continued this work alongside clinical training in acute medicine and neurology. I recently completed a Wellcome Trust Clinical Research Fellowship applying optogenetics to induced pluripotent stem cells from ALS patients to study activity-dependent mechanisms of motor neuron degeneration in C9ORF72 associated ALS, the commonest genetic subtype. 

I am now continuing my research with an NIHR Clinical Lectureship, with an ongoing focus on the role of motor neuron activity in ALS models and patients.