Contact information
Colleges
Research groups
Collaborators
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Simon Rinaldi
Associate Professor and Honorary Consultant Neurologist
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Alexander Davies
UKRI Future Leaders Fellow
Recent publications
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Guillain-Barré syndrome: A comprehensive review.
Journal article
Bellanti R. and Rinaldi S., (2024), Eur J Neurol
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Ultrasensitive assay technology and fluid biomarkers for the evaluation of peripheral nerve disease.
Journal article
Bellanti R. et al, (2023), J Neurol Neurosurg Psychiatry
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Reply: Peripherin is a biomarker of axonal damage in Guillain-Barré syndrome: a pathophysiological annotation
Journal article
Keddie S. et al, (2023), Brain
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AL amyloidosis presenting with isolated lumbosacral radiculoplexus neuropathy
Journal article
Bellanti R. et al, (2023), Practical Neurology
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Peripherin is a biomarker of axonal damage in peripheral nervous system disease
Journal article
Keddie S. et al, (2023), Brain
Roberto Bellanti
MBBS, MRCP, AFHEA
MRC Clinical Research Fellow
- DPhil candidate
- Honorary Neurology Registrar
- Public Engagement Ambassador
Biography
I am currently undertaking my doctoral training within the Oxford Inflammatory Neuropathy group. I am also an honorary neurology registrar at Oxford University Hospitals and previously undertook my clinical training between Cambridge, London, and the East of England.
Research
My research focuses on the immune-mediated neuropathies Guillain-Barré syndrome (GBS) and chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). These are conditions where the immune system, the body's natural defence against illness and infections, mistakenly attacks the nerves, causing progressive paralysis. In severe cases, people can lose their ability to walk, swallow and breathe. About 1 in 20 people with GBS die, and many are left with long-term disability.
I am working to develop serum peripheral nerve specific biomarker assays which I validate in vitro and clinically. I use cell-based models of antibody-mediated nerve injury and serum samples from patients with inflammatory neuropathies.
I hope my work will positively impact on both clinical and research aspects of the inflammatory neuropathies. Clinically, peripheral nerve specific biomarkers will assist with diagnosis, prognostication, monitoring of disease activity and titration of treatment. On a research level, they could be used as surrogate intermediate outcome measures, improving the efficiency of clinical trials and accelerating advances in care.