Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

DATE AND VENUE

Friday 26 June 2026, 1.30-6.30pm, TS Eliot Theatre, Merton College, Oxford.

Sponsored by the NIHR Biomedical Research Centre's Gene and Cell Therapy theme.

REGISTRATION

This event is open to Oxford University research staff and graduate students. Online registration is open until Wednesday 17 June 2026 via this registration form. Note that online registration may close before this date if all seats are filled. (An Oxford University Single Sign-On is required for access to the registration form.)

PROGRAMME

13.15 REGISTRATION
14.00 Robert MacLaren, Theme Leader for Gene and Cell Therapy, NIHR Oxford Biomedical Research Centre Welcoming address
14.05 SESSION 1: CRISPR gene editing, activation and silencing; applications of CRISPR in genome engineering (Chair: Silja Haldrup)
Silja Haldrup, Postdoctoral Researcher, Nuffield Department of Clinical Neurosciences Is prime editing a treatment strategy for retinal disease?
Tien-En Tan, DPhil Student and Clinical Research Fellow, Nuffield Department of Clinical Neurosciences Gene editing for dominant cone-rod dystrophy caused by mutations in GUCY2D
Gavin Turnbull, DPhil Student, Radcliffe Department of Medicine Navigating HITI optimisation: balancing CRISPR ratios and designing robust ddPCR assays
Steven Middleton, Senior Postdoctoral Researcher, Nuffield Department of Clinical Neurosciences Using CRISPR genome editing to link SLC45A4 to pain perception
Dagmara Korona, Postdoctoral Researcher, Radcliffe Department of Medicine Developing a mouse model of craniosynostosis using genome editing technologies
Divya Ail, Postdoctoral Researcher, Nuffield Department of Clinical Neurosciences Developing a non-human primate model of retinal degeneration using CRISPR-Cas9
15.30 COFFEE BREAK
16.00 SESSION 2: CRISPR screening, diagnostics and epigenetic modulation; preclinical development and clinical translation of CRISPR gene and cell therapies (Chair: Arjun Padmanabhan)
Arjun Padmanabhan, Postdoctoral Researcher, Nuffield Department of Clinical Neurosciences
HITing the right note: therapeutic genome editing for autosomal dominant retinitis pigmentosa due to RHO mutations (RP4)

Brent Ryan, Group Leader, Department of Physiology, Anatomy & Genetics

Functional genomics at scale using arrayed CRISPRi screening approaches in human neurons
Andrew Castle, Postdoctoral Researcher, Nuffield Department of Clinical Neurosciences Identifying modifiers of alpha-synuclein aggregation in Parkinson’s disease by proteostasis-focused CRISPR knockout screening
Ping Zhang, Senior Biostatistical Researcher, Centre for Human Genetics CRISPR strategies for editing regulatory genetic variation in immune cell crosstalk
Roman Doll, DPhil Student, Radcliffe Department of Medicine Genome editing for treatment of JAK2 V617F-driven myeloproliferative neoplasms
Sumana Sharma, Group Leader, Radcliffe Department of Medicine Genome-wide and arrayed KO strategies for primary T cells manipulation
17.15 DRINKS AND CANAPÉS