©
Shutterstock
Associate Professor Simon Rinaldi has received funding from the University of Oxford’s COVID-19 Research Response Fund to investigate this further. He and colleagues will compare the prevalence of SARS-CoV-2 polymerase chain reaction and seropositivity in a UK cohort of GBS patients identified during the pandemic, and compare GBS incidence rates to similar periods in previous years.
This will establish how often COVID-19 is complicated by GBS. By characterising COVID-GBS associated antibody and cytokine profiles, and evaluating their pathological effects in a myelinating culture model, the team will learn more about the underlying neuroimmunology of this disorder.