Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

Multiple recent case reports have suggested a link between COVID-19 and Guillain-Barré syndrome (GBS), an acute, disabling, immune-mediated disorder of the peripheral nervous system. It is currently unclear whether this simply represents a chance association.

© Shutterstock

Associate Professor Simon Rinaldi has received funding from the University of Oxford’s COVID-19 Research Response Fund to investigate this further. He and colleagues will compare the prevalence of SARS-CoV-2 polymerase chain reaction and seropositivity in a UK cohort of GBS patients identified during the pandemic, and compare GBS incidence rates to similar periods in previous years.

This will establish how often COVID-19 is complicated by GBS. By characterising COVID-GBS associated antibody and cytokine profiles, and evaluating their pathological effects in a myelinating culture model, the team will learn more about the underlying neuroimmunology of this disorder. 

Similar stories

Developmental dynamics of the neural crest–mesenchymal axis in creating the thymic microenvironment

A new paper from researchers at the Department of Paediatrics and the Nuffield Department of Clinical Neurosciences has shown that fibroblasts in the thymus, often considered simply as dull “structural” cells, are much more complex than previously thought.

How to use the science of the body clock to improve our sleep and health

Professor Russell Foster has written a new book about circadian neuroscience which is published by Penguin this week. This book review by Jacqueline Pumphrey was first published on the University of Oxford website.

Funding awarded for autoimmune disease research

Dr Kate Attfield awarded project funding by Connect Immune Research and The Lorna and Yuti Chernajovsky Biomedical Research Foundation.

Oxford researchers part of major UK initiative to understand chronic pain

Oxford pain researchers are playing a major role in a new multi-million pound research programme launched by a consortium of funders, including UKRI, Versus Arthritis, Eli Lilly and the Medical Research Foundation.

MRC BNDU receives a Wellcome Collaborative Award for Parkinson’s research

We are delighted to announce that the MRC Brain Network Dynamics Unit has received Collaborative Award funding from Wellcome for a substantial multi-year research programme designed to advance the understanding of why dopamine-producing nerve cells are especially vulnerable in Parkinson’s.