Fundamental biochemistry of N-glycosylation
The focus of this project is to better understand the mechanism and kinetics of N-glycosylation enzymes. This involves the large scale expression and purification of enzymes, and the chemical synthesis of the complex glycans and glycolipids. The mechanism and kinetics of the enzymes will then be assessed using biochemical methods and mass spectrometry. This project will be co-supervised by Prof Ben Davis of the Department of Chemistry.