Research groups
Colleges
Collaborators
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Heidi Johansen-Berg
Director of the Wellcome Centre for Integrative Neuroimaging; Associate Head of Medical Sciences Division (Research)
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Andrew Sharott
Associate Professor
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Tim Denison
Royal Academy of Engineering Chair in Emerging Technologies
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Melanie Fleming
Guarantors of Brain Research Fellow
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Sarosh Irani
Professor of Autoimmune Neurology
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Catharina Zich
Honorary Researcher
Charlotte Stagg
MRCP DPhil
Professor of Human Neurophysiology
- Wellcome Trust Senior Research Fellow
- Director of Studies for Preclinical Medicine, St Hilda's College
- Fellow by Special Election, St Edmund Hall
Physiological mechanisms of motor learning and recovery
I head the Physiological Neuroimaging Group.
My primary research interest is in understanding how the brain adapts to new challenges, focusing in particular in the physiological processes underlying the learning of new motor skills and in the recovery of motor function after stroke.
We take a multimodal approach to answer these questions, using advanced MR approaches, MEG, non-invasive brain stimulation and pharmacological agents. Our multidisciplinary team works on a wide variety of projects, with the ultimate aim of developing novel therapies to improve function in a range of neurological disorders.
We welcome enquires from potential DPhil (PhD) students and Postdoctoral Fellows - please email me.
For more details of our group's research please see our website.
Key publications
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A single, clinically relevant dose of the GABA
B
agonist baclofen impairs visuomotor learning
Journal article
Johnstone A. et al, (2021), The Journal of Physiology, 599, 307 - 322
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β-Oscillations Reflect Recovery of the Paretic Upper Limb in Subacute Stroke.
Journal article
Tang C-W. et al, (2020), Neurorehabil Neural Repair, 34, 450 - 462
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The dynamics of cortical GABA in human motor learning
Journal article
Kolasinski J. et al, (2019), The Journal of Physiology, 597, 271 - 282
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A Mechanistic Link from GABA to Cortical Architecture and Perception
Journal article
Kolasinski J. et al, (2017), Current Biology, 27, 1685 - 1691.e3
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Ipsilesional anodal tDCS enhances the functional benefits of rehabilitation in patients after stroke
Journal article
Allman C. et al, (2016), Science Translational Medicine, 8, 330re1 - 330re1
Recent publications
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Ramped V1 transcranial ultrasonic stimulation modulates but does not evoke visual evoked potentials
Preprint
Nandi T. et al, (2023)
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Transcranial focused ultrasound-mediated neurochemical and functional connectivity changes in deep cortical regions in humans
Preprint
Yaakub SN. et al, (2023)
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Three-layer model with absorption for conservative estimation of the maximum acoustic transmission coefficient through the human skull for transcranial ultrasound stimulation.
Journal article
Attali D. et al, (2022), Brain Stimul
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A mean-field model of glutamate and GABA synaptic dynamics for functional MRS.
Journal article
Lea-Carnall CA. et al, (2022), Neuroimage
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A macroscopic link between interhemispheric tract myelination and cortico-cortical interactions during action reprogramming
Journal article
Lazari A. et al, (2022), Nature Communications, 13
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Non-invasive brain stimulation modulates GABAergic activity in neurofibromatosis 1.
Journal article
Garg S. et al, (2022), Sci Rep, 12
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Cerebellar anodal tDCS does not facilitate visuomotor adaptation or retention.
Journal article
Nettekoven CR. et al, (2022), Brain Stimul, 15, 1435 - 1438
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Cerebellar GABA Change during Visuomotor Adaptation Relates to Adaptation Performance and Cerebellar Network Connectivity: A Magnetic Resonance Spectroscopic Imaging Study
Journal article
Nettekoven C. et al, (2022), Journal of Neuroscience, 42, 7721 - 7732
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tDCS induced GABA change is associated with the simulated electric field in M1, an effect mediated by grey matter volume in the MRS voxel.
Journal article
Nandi T. et al, (2022), Brain Stimul
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A checklist for assessing the methodological quality of concurrent tES-fMRI studies (ContES checklist): a consensus study and statement
Journal article
Ekhtiari H. et al, (2022), Nature Protocols, 17, 596 - 617