Cristina Martinez
BSc PhD
Postdoctoral Research Scientist
Cristina’s background is in retinal diseases and pharmacological therapies. She obtained her PhD at the Health Research Institute of the La Fe University Hospital (Valencia, Spain), where she studied the role of oxidative stress and inflammation in the pathogenesis of retinitis pigmentosa and the effect of anti-TNFα antibodies as a pharmacological approach to delay photoreceptor death.
Cristina is engaged in ongoing research to develop gene therapies for currently incurable retinal diseases such as retinitis pigmentosa or macular dystrophies, using modified forms of adeno-associated virus (AAV) as vectors to deliver therapeutic genes to retinal cells.
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Recent Publications
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Adalimumab Reduces Photoreceptor Cell Death in A Mouse Model of Retinal Degeneration
Martínez-Fernández de la Cámara C. et al, (2015), Scientific Reports, 5
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Infliximab reduces Zaprinast-induced retinal degeneration in cultures of porcine retina
Martínez-Fernández de la Cámara C. et al, (2014), Journal of Neuroinflammation, 11
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Altered Antioxidant-Oxidant Status in the Aqueous Humor and Peripheral Blood of Patients with Retinitis Pigmentosa
Martínez-Fernández de la Cámara C. et al, (2013), PLoS ONE, 8, e74223 - e74223
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Phosphodiesterase inhibition induces retinal degeneration, oxidative stress and inflammation in cone-enriched cultures of porcine retina
Martínez-Fernández de la Cámara C. et al, (2013), Experimental Eye Research, 111, 122 - 133