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Contact information


kanmin.xue@eye.ox.ac.uk

BIOGRAPHY

Kanmin Xue, MB BChir PhD FRCOphth, is a Wellcome Trust clinician scientist fellow at the University of Oxford and Honorary Consultant Vitreoretinal Surgeon at the Oxford Eye Hospital. He previously held the role of National Institute for Health Research (NIHR) Academic Clinical Lecturer in Oxford between 2014 and 2018, conducting laboratory and clinical research into gene therapy for inherited retinal diseases, robotic eye surgery and artificial retinal implant with Professor Robert MacLaren. He has completed the UK specialist training in ophthalmology and a vitreoretinal fellowship at the Royal Victorian Eye and Ear Hospital in Melbourne, Australia. He previously conducted PhD research at the MRC Laboratory of Molecular Biology in Cambridge into how DNA editing brings about antibody class switching, underwent clinical training at Trinity College Cambridge, and pre-clinical training at Brasenose College Oxford, where he was awarded Martin Wronker Prize for the top First Class in Medicine.

AWARDS

Ruskell Medal 2019

Ian Fraser Cup 2017

Luigi Barca Award 2017

Martin Wronker Prize in Medicine 2003

Social media

Websites

Kanmin Xue

MA MB BChir PhD FRCOphth

Wellcome Trust Clinical Research Career Development Fellow

  • Honorary Consultant Vitreoretinal Surgeon, Oxford University Hospitals NHS Foundation Trust & Great Ormond Street Hospital for Children, London
  • Member of Senior Common Room (former Medical Research Fellow), Corpus Christi College, Oxford

Research

The retina is an accessible part of the central nervous system and an ideal organ for studying neurodegeneration and assessing novel gene therapies. Kanmin leads the Retinal Disease and Repair Group, which is currently focused on investigating the mechanisms of retinal degeneration and inflammation in the context of age-related macular degeneration (AMD) and uveitis. Improved understanding of these diseases supports the development of novel therapeutic approaches, including viral and non-viral vector-mediated gene delivery, gene editing, and antisense oligonucleotide therapies. Clinical translation is aided by a multi-disciplinary approach, involving patient cohort studies, interventional clinical trials, and application of artificial intelligence (AI).

Team members

Joel Quinn, DPhil candidate & MRC Scholar (Merton College)

Molly John, DPhil candidate (Exeter College)

Monica Hu, DPhil candidate & Clarendon Scholar (Merton College)

Celia Sourd, Post-doctoral Research Scientist

Lakshanie Wickramasinghe, Post-doctoral Research Scientist & Knoop Junior Research Fellow in Ophthalmology (St Cross College)

Emer Chang, Academic Foundation Doctor (St Hugh's College)

  • Early Career Researcher Award, Oxford Ophthalmological Congress 2024

Past students

Laurel Chandler, DPhil (Merton College)

  • Thomas Willis Poster Prize 2019
  • Oxford-Bristol-Cardiff-Southampton Alliance in Vision Research Best Poster Prize 2017

Ayesha Musa, FHS student 2020 (Jesus College)

James Aylward, BM-BCh (St Hilda's College)

Dun Jack Fu, BM-BCh PhD (St Hugh's College)

Olivia Parham, FHS student 2016 (New College)

Howell Fu, FHS student 2015 (Exeter College)

Collaborators

Key publications

Recent publications

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